RPL35AP20

Across TCGA pan-cancer cohorts, RPL35AP20 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RPL35AP20 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RPL35AP20 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL35AP20 expression acts as an unfavorable survival marker, although some lineages such as BLCA and KIRP show a favorable association.

UCEC, OV, and BLCA are the cancer types where RPL35AP20 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	All	0.612	0.855	<.001	104	view →
OV	DFS	Tertile	II,III,IV	0.324	0.443	.004	52	view →
BLCA	DFS	Tertile	II,III,IV	0.422	0.278	.008	41	view →
CHOL	DFS	Median	II,III,IV	0.129	0.579	.001	39	view →
LIHC	DFS	Quartile	III,IV	0.141	0.520	<.001	36	view →
KIRP	OS	Quartile	III,IV	1.000	0.632	.001	17	view →
LUAD	OS	Tertile	All	0.778	0.870	.026	13	view →
BRCA	DFS	Median	All	0.879	0.923	.018	13	view →
STAD	OS	Median	All	0.625	0.740	.008	12	view →
DLBC	DFS	Median	III,IV	1.000	0.525	.013	12	view →
SKCM	DFS	Median	IV	0.596	0.276	.027	9	view →
PAAD	OS	Median	All	0.612	0.399	.021	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RPL35AP20–UCEC (OS)

Open the UCEC breakdown →