RPL35AP19

Across TCGA pan-cancer cohorts, RPL35AP19 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPL35AP19’s most consistent transcriptional readouts.

The strongest signal is observed in rectum adenocarcinoma (READ), where RPL35AP19 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL35AP19 is over-expressed in tumor, although a few such as READ and THCA show the opposite, repressed pattern.

READ, COAD, and THCA are the cancer types where RPL35AP19 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL35AP19 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
READ	All	III,IV	−0.245	.032	2	view →
COAD	All	II,III,IV	+0.118	.049	1	view →
THCA	All	II,III,IV	−0.060	.047	1	view →
KICH	All	All	−0.042	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RPL35AP19–READ

Open the READ breakdown →