RPL35AP17

Across TCGA pan-cancer cohorts, RPL35AP17 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RPL35AP17 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RPL35AP17 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPL35AP17 expression acts as an unfavorable survival marker, although some lineages such as COAD and SKCM show a favorable association.

KICH, KIRC, and COAD are the cancer types where RPL35AP17 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Quartile	All	0.506	0.957	<.001	42	view →
KIRC	DFS	Tertile	All	0.565	0.718	.003	42	view →
COAD	DFS	Quartile	II,III,IV	0.716	0.391	<.001	40	view →
ACC	DFS	Median	IV	0.174	0.480	.014	37	view →
SKCM	OS	Quartile	All	0.934	0.724	.001	25	view →
THCA	DFS	Median	All	0.695	0.916	.017	19	view →
LUAD	DFS	Tertile	II,III,IV	0.781	0.572	.024	10	view →
THYM	DFS	Tertile	IV	0.407	1.000	.026	9	view →
LIHC	DFS	Quartile	All	0.352	0.462	.026	7	view →
PAAD	DFS	Median	II,III,IV	0.365	0.500	.024	6	view →
KIRP	OS	Median	II,III,IV	0.363	0.706	.026	6	view →
TGCT	DFS	Median	II,III,IV	0.778	1.000	.046	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RPL35AP17–KICH (DFS)

Open the KICH breakdown →