RPL35AP14

Across TCGA pan-cancer cohorts, RPL35AP14 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RPL35AP14 data layer.

The strongest signal is observed in acute myeloid leukemia (LAML), where higher RPL35AP14 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RPL35AP14 expression acts as an unfavorable survival marker, although some lineages such as LAML and GBM show a favorable association.

LAML, KICH, and GBM are the cancer types where RPL35AP14 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LAML	DFS	Median	All	0.619	0.292	<.001	54	view →
KICH	DFS	Quartile	II,III,IV	0.285	0.914	<.001	44	view →
GBM	OS	Tertile	All	0.777	0.358	.020	18	view →
OV	DFS	Tertile	IV	0.291	0.518	.005	18	view →
PCPG	OS	Tertile	All	0.904	1.000	.005	18	view →
READ	DFS	Tertile	IV	0.910	0.482	.026	15	view →
BRCA	OS	Tertile	III,IV	0.960	0.873	.010	8	view →
THYM	OS	Tertile	II,III,IV	0.359	0.878	.028	6	view →
KIRC	OS	Tertile	All	0.912	0.861	.018	5	view →
THCA	DFS	Median	All	0.765	0.879	.035	4	view →
COAD	OS	Tertile	All	0.721	0.827	.041	3	view →
LIHC	DFS	Tertile	All	0.142	0.322	.047	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RPL35AP14–LAML (DFS)

Open the LAML breakdown →