RPL35A

Across TCGA cell cohorts, RPL35A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,364 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RPL35A-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Protein linear polyubiquitination, and tRNA 5'-end processing. Each is linked with RPL35A in more than 13 cancer types. Because this analysis shows association rather than direction, both RPL35A-to-partner and partner-to-RPL35A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by RPL35A-low versus RPL35A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL35A→partner) and Y-score (partner→RPL35A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of calcium ion export across plasma membrane →	-0.106	-1.134	<.001	<.001	3	14
OVARY	Protein linear polyubiquitination →	-0.148	-0.864	<.001	<.001	3	13
BONE	tRNA 5'-end processing →	+0.126	+0.845	<.001	.001	3	13
KIDNEY	Regulation of pattern recognition receptor signaling pathway →	-0.069	-0.810	<.001	<.001	3	13
KIDNEY	Assembly of actomyosin apparatus involved in cytokinesis →	-0.206	-0.873	.001	<.001	3	12
KIDNEY	Actomyosin contractile ring assembly →	-0.206	-0.873	.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,364 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by RPL35A expression — BONE

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