RPL35

Across TCGA patient cohorts, RPL35 mutation is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL35-associated genes across cancer lineages are RNU6-618P, REXO1L8P, and MIR6784. Each is linked with RPL35 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL35-to-partner and partner-to-RPL35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-618P grouped by RPL35-low versus RPL35-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL35→partner) and Y-score (partner→RPL35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-618P →	+0.401	+3.384	.002	.002	3	2
BLCA	REXO1L8P →	+0.096	+5.497	<.001	.004	3	2
UCEC	MIR6784 →	+1.105	+3.361	.002	.008	3	1
COAD	OR4X2 →	+0.054	+7.741	<.001	.009	3	1
UCEC	SNORD114-7 →	+0.303	+4.292	.003	.006	3	1
UCEC	RNU6-582P →	+0.366	+4.660	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

RNU6-618P by RPL35 expression — UCEC

Explore this box plot interactively →