RPL34P8

Across TCGA pan-cancer cohorts, RPL34P8 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RPL34P8’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RPL34P8 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL34P8 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

THCA, BRCA, and KIRP are the cancer types where RPL34P8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL34P8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.126	.013	4	view →
BRCA	Female	All	+0.062	.030	2	view →
KIRP	All	All	+0.042	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RPL34P8–THCA

Open the THCA breakdown →