RPL34P6

Across TCGA pan-cancer cohorts, RPL34P6 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RPL34P6’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RPL34P6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL34P6 is over-expressed in tumor, although a few such as BRCA and KICH show the opposite, repressed pattern.

COAD, KIRC, and CHOL are the cancer types where RPL34P6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL34P6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.300	.005	5	view →
KIRC	All	II,III,IV	+0.116	.020	4	view →
CHOL	All	All	+0.544	.004	2	view →
READ	Male	All	+0.523	.015	2	view →
BRCA	All	III,IV	−0.218	.047	2	view →
HNSC	Male	All	+0.201	.005	2	view →
LIHC	All	II,III,IV	+0.100	.033	2	view →
KICH	Female	III,IV	−0.206	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

RPL34P6–COAD

Open the COAD breakdown →