Across TCGA pan-cancer cohorts, RPL34P23 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RPL34P23’s most consistent transcriptional readouts.
The strongest signal is observed in prostate adenocarcinoma (PRAD), where RPL34P23 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL34P23 is over-expressed in tumor.
PRAD, LIHC, and COAD are the cancer types where RPL34P23 tumor–normal differential expression is most reproducible.