RPL34P18

Across TCGA pan-cancer cohorts, RPL34P18 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RPL34P18’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RPL34P18 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL34P18 is over-expressed in tumor, although a few such as BRCA and STAD show the opposite, repressed pattern.

COAD, KIRC, and BRCA are the cancer types where RPL34P18 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL34P18 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+1.306	<.001	6	view →
KIRC	Male	All	+0.298	<.001	6	view →
BRCA	Female	All	−0.213	.011	4	view →
STAD	Male	III,IV	−0.594	.038	2	view →
KICH	Male	II,III,IV	+0.416	.031	2	view →
THCA	All	II,III,IV	+0.278	.030	2	view →
LUAD	All	All	+0.240	.041	2	view →
KICH	Female	All	−0.367	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 7 lineages.

RPL34P18–COAD

Open the COAD breakdown →