Across TCGA pan-cancer cohorts, RPL34P1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPL34P1’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RPL34P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL34P1 is over-expressed in tumor.
HNSC and KIRC are the cancer types where RPL34P1 tumor–normal differential expression is most reproducible.