RPL34

Across TCGA patient cohorts, RPL34 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL34-associated genes across cancer lineages are AQP7P4, MIR8082, and AQP7P3. Each is linked with RPL34 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL34-to-partner and partner-to-RPL34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AQP7P4 grouped by RPL34-low versus RPL34-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL34→partner) and Y-score (partner→RPL34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AQP7P4 →	+0.122	+5.027	<.001	.004	3	1
UCEC	MIR8082 →	+0.991	+5.146	<.001	.001	3	1
UCEC	AQP7P3 →	+0.117	+5.582	<.001	.002	3	1
UCEC	RPSAP64 →	+0.352	+4.499	<.001	.005	3	1
UCEC	RNU6-1213P →	+0.528	+5.877	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

AQP7P4 by RPL34 expression — UCEC

Explore this box plot interactively →