RPL32P21

Across TCGA pan-cancer cohorts, RPL32P21 mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPL32P21’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RPL32P21 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types RPL32P21 is over-expressed in tumor, although a few such as COAD and LSCC show the opposite, repressed pattern.

COAD, PDAC, and LSCC are the cancer types where RPL32P21 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL32P21 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	III,IV	−0.922	<.001	9	view →
PDAC	Male	All	+1.068	<.001	7	view →
LSCC	Male	III,IV	−1.345	<.001	6	view →
LUAD	All	All	−0.627	.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RPL32P21–COAD

Open the COAD breakdown →