RPL31P57

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RPL31P57 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible RPL31P57-associated genes across cancer lineages are SC4MOP, RNU6-1273P, and SNORD115-22. Each is linked with RPL31P57 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL31P57-to-partner and partner-to-RPL31P57 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SC4MOP grouped by RPL31P57-low versus RPL31P57-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL31P57→partner) and Y-score (partner→RPL31P57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSC4MOP →+0.153+6.453<.001.00132
BLCARNU6-1273P →+0.373+7.640<.001.00931
BLCASNORD115-22 →+0.448+7.640<.001.00931
BLCARNA5SP380 →+0.393+7.640<.001.00931
BLCAPPATP2 →+0.099+7.640<.001.00931
BLCAPMS2P8 →+0.074+7.640<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

SC4MOP by RPL31P57 expression — UCEC

Box plot of SC4MOP in RPL31P57-low vs RPL31P57-high samples in UCEC.

Explore this box plot interactively →

Exploration