RPL31P53

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RPL31P53 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RPL31P53 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RPL31P53 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL31P53 expression acts as an unfavorable survival marker, although some lineages such as LGG show a favorable association.

BRCA, STAD, and ESCA are the cancer types where RPL31P53 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSTertileAll0.2000.582<.001102view →
STADDFSTertileAll0.1210.509<.00163view →
ESCAOSTertileIV0.0950.512.00839view →
LUSCOSTertileAll0.5920.781.01436view →
LIHCOSTertileAll0.0610.783<.00136view →
UCECDFSTertileAll0.2400.676<.00136view →
LGGOSTertileAll0.6680.423.00715view →
SKCMOSTertileAll0.4860.789.0466view →
Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

Exploration