Across TCGA pan-cancer cohorts, RPL31P47 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RPL31P47’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where RPL31P47 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL31P47 is over-expressed in tumor, although a few such as BRCA and LUSC show the opposite, repressed pattern.
BRCA, LUSC, and THCA are the cancer types where RPL31P47 tumor–normal differential expression is most reproducible.