Across TCGA pan-cancer cohorts, RPL31P45 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPL31P45’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where RPL31P45 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL31P45 is over-expressed in tumor.
BRCA and KIRC are the cancer types where RPL31P45 tumor–normal differential expression is most reproducible.