RPL31P40

Across TCGA pan-cancer cohorts, RPL31P40 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPL31P40’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where RPL31P40 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL31P40 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and KICH are the cancer types where RPL31P40 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL31P40 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	II,III,IV	−0.843	<.001	9	view →
LUSC	Female	II,III,IV	−0.695	<.001	8	view →
KICH	All	All	−0.054	.009	3	view →
PRAD	All	All	+0.138	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RPL31P40–LUAD

Open the LUAD breakdown →