RPL31P30

Across TCGA pan-cancer cohorts, RPL31P30 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RPL31P30’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RPL31P30 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL31P30 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, KICH, and KIRC are the cancer types where RPL31P30 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL31P30 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	−1.408	<.001	10	view →
KICH	Male	II,III,IV	−0.902	<.001	10	view →
KIRC	All	IV	−0.303	.021	5	view →
LIHC	Male	All	+0.100	.004	4	view →
ESCA	All	II,III,IV	+0.499	.029	2	view →
LUSC	Female	All	+0.441	.004	2	view →
KIRP	Female	II,III,IV	−0.384	.028	2	view →
LUAD	All	All	−0.209	.011	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

RPL31P30–THCA

Open the THCA breakdown →