Across TCGA pan-cancer cohorts, RPL31P28 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RPL31P28’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPL31P28 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL31P28 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

KIRC, COAD, and HNSC are the cancer types where RPL31P28 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL31P28 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+0.106	<.001	5	view →
COAD	All	II,III,IV	+0.367	.002	4	view →
HNSC	Female	II,III,IV	+0.095	.008	2	view →
LIHC	All	All	+0.040	.036	2	view →
THCA	Male	All	−0.151	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: RPL31P28 RNA expression & survival · all RPL31P28 data types