RPL31P12

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RPL31P12 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RPL31P12 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RPL31P12 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPL31P12 expression acts as an unfavorable survival marker, although some lineages such as THYM and BLCA show a favorable association.

UCEC, ACC, and THYM are the cancer types where RPL31P12 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECDFSTertileAll0.7650.867<.00190view →
ACCOSQuartileII,III,IV0.6050.949<.00150view →
THYMDFSTertileII,III,IV0.9750.765.00234view →
UCSDFSMedianIII,IV0.1310.457.01034view →
STADOSMedianAll0.4590.640.00431view →
KIRPDFSTertileAll0.7440.902<.00127view →
BLCADFSQuartileII,III,IV0.6100.468.01224view →
CESCDFSQuartileAll0.7250.460.02220view →
LUADOSQuartileIII,IV0.1910.631<.00114view →
KIRCDFSQuartileIV0.2320.569.02512view →
LGGOSMedianAll0.9460.841<.00111view →
UVMDFSQuartileAll0.8510.510.0096view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

Exploration