RPL31

Across TCGA patient cohorts, RPL31 protein abundance is significantly associated with the RNA expression of many other genes, with 16,323 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible RPL31-associated genes across cancer lineages are FCGR3B, CXCR2, and CMTM2. Each is linked with RPL31 in more than 6 cancer types. Because this analysis shows association rather than direction, both RPL31-to-partner and partner-to-RPL31 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPL31 versus FCGR3B in PDAC, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL31→partner) and Y-score (partner→RPL31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	FCGR3B →	-1.373	-0.390	<.001	<.001	3	7
PDAC	CXCR2 →	-0.827	-0.379	<.001	<.001	3	7
COAD	CMTM2 →	-0.688	-0.306	<.001	<.001	3	5
COAD	CXCL8 →	-1.680	-0.223	<.001	.002	3	5
PDAC	CXCR1 →	-0.840	-0.332	<.001	<.001	3	5
HNSC	RENBP →	-1.074	-0.426	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,323 associations by consensus.

RPL31 vs FCGR3B — PDAC

Explore this scatter interactively →