RPL31

Across TCGA patient cohorts, RPL31 mutation is significantly associated with the RNA expression of many other genes, with 431 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL31-associated genes across cancer lineages are RN7SKP181, AQP7P3, and RN7SL32P. Each is linked with RPL31 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL31-to-partner and partner-to-RPL31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP181 grouped by RPL31-low versus RPL31-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL31→partner) and Y-score (partner→RPL31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP181 →	+0.150	+2.963	<.001	.003	3	2
UCEC	AQP7P3 →	+0.043	+3.845	<.001	.001	3	1
UCEC	RN7SL32P →	+0.331	+3.284	.003	<.001	3	1
UCEC	MIR548AI →	+0.217	+4.276	<.001	.005	3	1
UCEC	FBXO7 →	+0.570	+3.606	<.001	.001	3	1
UCEC	PACSIN2 →	+0.605	+3.584	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 431 associations by consensus.

RN7SKP181 by RPL31 expression — UCEC

Explore this box plot interactively →