Across TCGA pan-cancer cohorts, RPL30P1 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of RPL30P1’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where RPL30P1 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL30P1 is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.
STAD are the cancer types where RPL30P1 tumor–normal differential expression is most reproducible.