RPL3

Across TCGA cell cohorts, RPL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,309 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RPL3-associated GO terms across cancer lineages are Transcription initiation at mitochondrial promoter, Protein exit from endoplasmic reticulum, and Negative regulation of protein catabolic process. Each is linked with RPL3 in more than 12 cancer types. Because this analysis shows association rather than direction, both RPL3-to-partner and partner-to-RPL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription initiation at mitochondrial promoter grouped by RPL3-low versus RPL3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL3→partner) and Y-score (partner→RPL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Transcription initiation at mitochondrial promoter →	+0.132	+0.681	<.001	<.001	3	13
LIVER	Protein exit from endoplasmic reticulum →	-0.127	-0.692	<.001	.003	3	12
LIVER	Negative regulation of protein catabolic process →	-0.088	-0.777	.001	<.001	3	12
BREAST	Response to unfolded protein →	-0.084	-0.733	<.001	<.001	3	11
LARGE_INTESTINE	Proteinogenic amino acid metabolic process →	+0.108	+0.667	<.001	<.001	3	11
CNS	Wound healing →	-0.103	-0.667	<.001	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,309 associations by consensus.

Transcription initiation at mitochondrial promoter by RPL3 expression — OVARY

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