Across TCGA pan-cancer cohorts, RPL29P22 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPL29P22’s most consistent transcriptional readouts.
The strongest signal is observed in prostate adenocarcinoma (PRAD), where RPL29P22 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL29P22 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.
PRAD and KICH are the cancer types where RPL29P22 tumor–normal differential expression is most reproducible.