RPL27P8

Across TCGA pan-cancer cohorts, RPL27P8 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPL27P8’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RPL27P8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL27P8 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

HNSC and COAD are the cancer types where RPL27P8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL27P8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.053	.001	8	view →
COAD	Male	II,III,IV	−0.095	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

RPL27P8–HNSC

Open the HNSC breakdown →