Q-omics provides the consensus-scored RPL27P6 profile across patient tissues and cancer cell-line models. RPL27P6 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, RPL27P6 is differentially expressed in 7, with the highest sampling consensus in COAD. Additionally, RPL27P6 RNA expression shows 9,419 significant gene co-expression associations, with the highest sampling consensus in READ. Together, these results highlight ACC, COAD, and READ as cancer lineages where RPL27P6 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPL27P6 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPL27P6 survival associations across molecular data types. RPL27P6 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPL27P6 RNA expression–survival associations across cancer types. High RPL27P6 expression shows unfavorable associations in ACC, PAAD and STAD, but favorable associations in HNSC, THCA and COAD. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify ACC as the clearest survival context for RPL27P6 RNA expression.
This table summarizes RPL27P6 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 7. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for RPL27P6. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPL27P6 shows lower tumor expression in BRCA and higher tumor expression in COAD, LUAD, LIHC, READ and KIRC. The COAD box plot shows higher RPL27P6 RNA expression in tumor versus normal tissue (log2 FC = +1.081, t-test p < 0.001).
This table shows molecular features associated with RPL27P6 in patient tissues and cancer cell lines. In patient samples, RPL27P6 shows the broadest associations at the RNA and protein expression levels, with READ recurring as the lineage with the largest associated feature set.
