RPL27P12

Across TCGA pan-cancer cohorts, RPL27P12 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPL27P12’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPL27P12 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL27P12 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

KIRC and COAD are the cancer types where RPL27P12 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL27P12 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	−0.026	.008	3	view →
COAD	All	All	+0.080	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

RPL27P12–KIRC

Open the KIRC breakdown →