RPL27AP3

Across TCGA pan-cancer cohorts, RPL27AP3 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RPL27AP3 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RPL27AP3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPL27AP3 expression acts as an unfavorable survival marker, although some lineages such as CESC and BLCA show a favorable association.

LUAD, ACC, and THYM are the cancer types where RPL27AP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	III,IV	0.268	0.560	.009	69	view →
ACC	DFS	Tertile	III,IV	0.169	0.510	.014	54	view →
THYM	DFS	Quartile	All	0.693	0.927	.002	51	view →
OV	DFS	Median	All	0.128	0.193	.006	36	view →
LIHC	OS	Tertile	III,IV	0.184	0.397	.011	24	view →
KIRP	DFS	Tertile	IV	0.154	0.548	<.001	18	view →
KIRC	DFS	Tertile	IV	0.221	0.603	.046	18	view →
THCA	OS	Tertile	IV	0.751	1.000	.014	15	view →
CESC	OS	Tertile	II,III,IV	0.840	0.483	.048	12	view →
COAD	OS	Tertile	All	0.444	0.724	.021	12	view →
BLCA	OS	Tertile	III,IV	0.751	0.515	.018	9	view →
SKCM	OS	Tertile	III,IV	1.000	0.669	.020	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RPL27AP3–LUAD (DFS)

Open the LUAD breakdown →