RPL26L1

Across TCGA pan-cancer cohorts, RPL26L1 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated RPL26L1 data layer compared with 27 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RPL26L1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RPL26L1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and COAD show a favorable association.

UCEC, PDAC, and CCRCC are the cancer types where RPL26L1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	III,IV	1.000	0.386	.002	48	view →
PDAC	DFS	Quartile	II,III,IV	0.722	0.990	.002	14	view →
CCRCC	DFS	Median	III,IV	0.418	0.696	.008	14	view →
COAD	DFS	Tertile	II,III,IV	1.000	0.907	.042	12	view →
GBM	DFS	Quartile	All	0.397	0.744	.022	4	view →
HNSC	OS	Median	All	1.000	0.520	.040	4	view →
LSCC	DFS	Tertile	All	0.786	0.593	.049	1	view →
LUAD	OS	Tertile	All	0.958	1.000	.041	1	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RPL26L1–UCEC (DFS)

Open the UCEC breakdown →