RPL26L1

Across TCGA patient cohorts, RPL26L1 mutation is significantly associated with the RNA expression of many other genes, with 164 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL26L1-associated genes across cancer lineages are RNA5SP516, MIR527, and SQSTM1P1. Each is linked with RPL26L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL26L1-to-partner and partner-to-RPL26L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP516 grouped by RPL26L1-low versus RPL26L1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL26L1→partner) and Y-score (partner→RPL26L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP516 →	+0.222	+3.200	.001	.006	3	2
UCEC	MIR527 →	+0.396	+3.953	<.001	<.001	3	2
UCEC	SQSTM1P1 →	+0.072	+2.861	<.001	.004	3	2
STAD	MIR3924 →	+0.406	+5.105	<.001	.008	3	1
BLCA	RNU1-55P →	+0.324	+5.788	<.001	.003	3	1
LUSC	RNU4-13P →	+0.448	+6.081	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 164 associations by consensus.

RNA5SP516 by RPL26L1 expression — UCEC

Explore this box plot interactively →