RPL26L1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RPL26L1 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL26L1-associated genes across cancer lineages are JNK2 and Notch1. Each is linked with RPL26L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL26L1-to-partner and partner-to-RPL26L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK2 grouped by RPL26L1-low versus RPL26L1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL26L1→partner) and Y-score (partner→RPL26L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECJNK2 →+0.258+3.321.013.01011
UCECNotch1 →+0.151+3.321.041.01011
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

JNK2 by RPL26L1 expression — UCEC

Box plot of JNK2 in RPL26L1-low vs RPL26L1-high samples in UCEC.

Explore this box plot interactively →

Exploration