RPL23AP97

Across TCGA pan-cancer cohorts, RPL23AP97 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RPL23AP97 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RPL23AP97 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPL23AP97 expression acts as an unfavorable survival marker, although some lineages such as UCS and LUAD show a favorable association.

HNSC, ACC, and UVM are the cancer types where RPL23AP97 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	II,III,IV	0.576	0.760	.001	71	view →
ACC	OS	Quartile	II,III,IV	0.654	1.000	.002	59	view →
UVM	OS	Tertile	All	0.421	0.853	.006	37	view →
UCS	OS	Median	IV	0.732	0.224	.018	24	view →
KIRP	DFS	Tertile	IV	0.036	0.526	.006	22	view →
LUAD	DFS	Tertile	II,III,IV	0.384	0.238	.011	18	view →
UCEC	DFS	Quartile	All	0.778	0.887	.012	18	view →
OV	OS	Tertile	III,IV	0.252	0.374	.008	16	view →
SKCM	OS	Tertile	III,IV	0.604	0.254	.005	15	view →
MESO	OS	Quartile	All	0.345	0.610	.004	14	view →
CHOL	OS	Quartile	All	0.668	1.000	.022	11	view →
SARC	OS	Quartile	All	0.748	0.971	.003	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RPL23AP97–HNSC (DFS)

Open the HNSC breakdown →