Across TCGA pan-cancer cohorts, RPL23AP96 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPL23AP96’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where RPL23AP96 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL23AP96 is over-expressed in tumor.
COAD and READ are the cancer types where RPL23AP96 tumor–normal differential expression is most reproducible.