RPL23AP94

Across TCGA pan-cancer cohorts, RPL23AP94 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RPL23AP94’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RPL23AP94 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL23AP94 is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

BRCA, COAD, and LUAD are the cancer types where RPL23AP94 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL23AP94 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	−0.138	<.001	6	view →
COAD	All	All	+0.270	.004	4	view →
LUAD	All	All	+0.029	.016	2	view →
HNSC	All	II,III,IV	+0.022	.043	2	view →
THCA	All	All	−0.024	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RPL23AP94–BRCA

Open the BRCA breakdown →