Across TCGA pan-cancer cohorts, RPL23AP82 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of RPL23AP82’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPL23AP82 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL23AP82 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.
KIRC, THCA, and LIHC are the cancer types where RPL23AP82 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL23AP82 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.