RPL23AP78

Across TCGA pan-cancer cohorts, RPL23AP78 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPL23AP78’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where RPL23AP78 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL23AP78 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

KIRP, KIRC, and LUSC are the cancer types where RPL23AP78 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL23AP78 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	II,III,IV	+0.094	.001	5	view →
KIRC	All	All	+0.038	.008	5	view →
LUSC	All	III,IV	−0.155	.034	2	view →
BRCA	All	II,III,IV	+0.043	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RPL23AP78–KIRP

Open the KIRP breakdown →