RPL23AP69

Across TCGA pan-cancer cohorts, RPL23AP69 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RPL23AP69’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPL23AP69 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL23AP69 is over-expressed in tumor, although a few such as UCEC and LUSC show the opposite, repressed pattern.

KIRC, UCEC, and LUSC are the cancer types where RPL23AP69 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL23AP69 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+0.056	.006	3	view →
UCEC	All	All	−0.111	.040	2	view →
LUSC	Female	II,III,IV	−0.118	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RPL23AP69–KIRC

Open the KIRC breakdown →