RPL23AP64

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RPL23AP64 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RPL23AP64 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher RPL23AP64 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL23AP64 expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

THCA, KICH, and LUAD are the cancer types where RPL23AP64 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
THCAOSTertileII,III,IV0.9101.000.00366view →
KICHOSMedianII,III,IV0.7611.000.00752view →
LUADOSMedianAll0.8540.774.01138view →
UVMDFSQuartileII,III,IV0.3740.816.00937view →
LGGDFSTertileAll0.7550.889<.00132view →
HNSCDFSMedianIV0.3920.250.01127view →
READOSQuartileAll1.0000.385.00226view →
UCSDFSMedianIV0.9520.367.00124view →
SKCMOSMedianIII,IV0.7900.581<.00122view →
LUSCDFSMedianIII,IV0.5690.741.02217view →
ACCDFSQuartileAll0.4180.856.01516view →
CESCDFSMedianAll0.7680.877.00416view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RPL23AP64–THCA (OS)

Kaplan–Meier survival curve for RPL23AP64 RNA-high vs -low samples in THCA.

Open the THCA breakdown →

Exploration