RPL23AP63

Across TCGA pan-cancer cohorts, RPL23AP63 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RPL23AP63 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RPL23AP63 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPL23AP63 expression acts as an unfavorable survival marker, although some lineages such as UCS and THCA show a favorable association.

ACC, OV, and PAAD are the cancer types where RPL23AP63 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.250	0.625	<.001	111	view →
OV	OS	Quartile	II,III,IV	0.239	0.388	<.001	86	view →
PAAD	DFS	Median	All	0.356	0.631	<.001	42	view →
KIRP	DFS	Tertile	II,III,IV	0.164	0.729	.001	39	view →
UCS	DFS	Median	IV	0.885	0.440	.015	26	view →
COAD	OS	Median	IV	0.230	0.844	.003	25	view →
MESO	OS	Median	III,IV	0.418	0.700	<.001	20	view →
KICH	OS	Tertile	II,III,IV	0.878	1.000	.008	19	view →
LUAD	DFS	Median	All	0.273	0.437	.005	15	view →
THCA	OS	Tertile	All	0.973	0.882	.014	12	view →
SKCM	OS	Tertile	III,IV	0.883	0.753	.015	8	view →
LIHC	OS	Tertile	All	0.696	0.853	.011	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RPL23AP63–ACC (DFS)

Open the ACC breakdown →