RPL23AP61

Across TCGA pan-cancer cohorts, RPL23AP61 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RPL23AP61 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RPL23AP61 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL23AP61 expression acts as an unfavorable survival marker, although some lineages such as BRCA and LAML show a favorable association.

KICH, BRCA, and UVM are the cancer types where RPL23AP61 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Quartile	III,IV	0.125	0.794	<.001	39	view →
BRCA	OS	Median	III,IV	0.657	0.454	.009	29	view →
UVM	DFS	Quartile	All	0.472	0.869	.019	29	view →
LAML	DFS	Quartile	All	0.775	0.449	<.001	28	view →
CHOL	OS	Tertile	II,III,IV	0.186	0.743	.007	18	view →
LUAD	DFS	Tertile	All	0.749	0.607	.009	17	view →
ACC	OS	Median	III,IV	0.808	0.421	.012	16	view →
UCEC	DFS	Tertile	All	0.792	0.882	.003	14	view →
UCS	DFS	Tertile	IV	0.996	0.550	.033	12	view →
OV	OS	Median	III,IV	0.283	0.355	.017	10	view →
READ	OS	Median	III,IV	1.000	0.752	.013	10	view →
LIHC	OS	Tertile	III,IV	0.180	0.487	.007	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RPL23AP61–KICH (OS)

Open the KICH breakdown →