RPL23AP56

Across TCGA pan-cancer cohorts, RPL23AP56 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated RPL23AP56 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher RPL23AP56 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPL23AP56 expression acts as an unfavorable survival marker, although some lineages such as KIRP and LUAD show a favorable association.

UCS, DLBC, and LGG are the cancer types where RPL23AP56 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	IV	0.132	0.718	.002	108	view →
DLBC	DFS	Tertile	III,IV	0.118	0.774	<.001	63	view →
LGG	OS	Median	All	0.707	0.865	<.001	48	view →
READ	OS	Tertile	All	0.166	0.830	<.001	36	view →
LIHC	DFS	Tertile	III,IV	0.087	0.337	.001	24	view →
STAD	DFS	Tertile	III,IV	0.297	0.650	.002	18	view →
TGCT	OS	Tertile	All	0.845	0.967	.022	18	view →
ESCA	OS	Tertile	All	0.492	0.719	.031	12	view →
COAD	OS	Tertile	All	0.193	0.676	.026	12	view →
PCPG	OS	Tertile	All	0.906	0.985	.018	12	view →
BRCA	OS	Tertile	IV	0.351	0.653	.029	9	view →
MESO	OS	Tertile	IV	0.256	0.640	.017	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

RPL23AP56–UCS (DFS)

Open the UCS breakdown →