RPL23AP52

Across TCGA pan-cancer cohorts, RPL23AP52 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RPL23AP52’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RPL23AP52 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL23AP52 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

COAD, BRCA, and KIRC are the cancer types where RPL23AP52 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL23AP52 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+0.280	.004	4	view →
BRCA	All	All	+0.148	.010	4	view →
KIRC	All	All	+0.056	<.001	4	view →
HNSC	Male	All	+0.077	.014	3	view →
PRAD	All	All	+0.081	.009	2	view →
LUAD	All	All	+0.259	.017	1	view →
KICH	Female	All	−0.105	.024	1	view →
LUSC	All	All	+0.057	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

RPL23AP52–COAD

Open the COAD breakdown →