RPL23AP50

Across TCGA pan-cancer cohorts, RPL23AP50 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated RPL23AP50 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RPL23AP50 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL23AP50 expression acts as an unfavorable survival marker, although some lineages such as UCS and HNSC show a favorable association.

KIRC, UCS, and PCPG are the cancer types where RPL23AP50 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.544	0.690	<.001	48	view →
UCS	OS	Quartile	II,III,IV	0.726	0.271	.006	38	view →
PCPG	DFS	Tertile	All	0.500	0.837	.008	18	view →
DLBC	DFS	Tertile	III,IV	0.137	0.790	<.001	18	view →
UVM	OS	Tertile	All	0.399	0.774	.020	18	view →
LIHC	OS	Tertile	All	0.687	0.802	.025	18	view →
THCA	OS	Quartile	IV	0.771	1.000	.011	16	view →
HNSC	DFS	Quartile	IV	0.402	0.268	.008	14	view →
BLCA	DFS	Median	IV	0.365	0.155	.015	12	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	9	view →
ACC	OS	Tertile	IV	0.291	0.596	.046	9	view →
LGG	DFS	Quartile	All	0.708	0.860	<.001	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

RPL23AP50–KIRC (OS)

Open the KIRC breakdown →