Across TCGA pan-cancer cohorts, RPL23AP46 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RPL23AP46’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where RPL23AP46 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL23AP46 is over-expressed in tumor.

LUAD, KIRC, and COAD are the cancer types where RPL23AP46 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL23AP46 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	All	+0.088	.008	3	view →
KIRC	Male	All	+0.033	.036	2	view →
COAD	Female	IV	+0.350	.003	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: RPL23AP46 RNA expression & survival · all RPL23AP46 data types