RPL23AP35

Across TCGA pan-cancer cohorts, RPL23AP35 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RPL23AP35 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RPL23AP35 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPL23AP35 expression acts as an unfavorable survival marker, although some lineages such as READ and LUAD show a favorable association.

MESO, CHOL, and UCEC are the cancer types where RPL23AP35 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Tertile	All	0.180	0.406	<.001	72	view →
CHOL	OS	Tertile	All	0.258	0.674	.010	45	view →
UCEC	OS	Tertile	II,III,IV	0.773	0.874	.010	42	view →
READ	DFS	Tertile	II,III,IV	0.899	0.748	.019	32	view →
STAD	DFS	Tertile	IV	0.216	0.783	.011	16	view →
OV	OS	Quartile	All	0.628	0.696	.015	16	view →
LUAD	DFS	Quartile	All	0.551	0.320	.008	13	view →
PAAD	DFS	Tertile	II,III,IV	0.764	0.419	.029	12	view →
SKCM	OS	Tertile	III,IV	0.767	0.333	.013	12	view →
UVM	DFS	Tertile	All	0.617	0.368	.033	10	view →
LAML	DFS	Tertile	All	0.685	0.488	.024	6	view →
BRCA	DFS	Tertile	III,IV	0.933	0.849	.029	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RPL23AP35–MESO (DFS)

Open the MESO breakdown →