RPL23AP32

Across TCGA pan-cancer cohorts, RPL23AP32 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RPL23AP32’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where RPL23AP32 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL23AP32 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and BRCA are the cancer types where RPL23AP32 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL23AP32 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	II,III,IV	−1.159	<.001	7	view →
LUSC	Female	All	−0.834	<.001	6	view →
BRCA	All	III,IV	−0.823	<.001	6	view →
UCEC	All	II,III,IV	−0.586	.006	6	view →
BLCA	All	All	−0.383	.013	6	view →
KICH	All	All	−0.110	.012	4	view →
ESCA	Female	All	−0.503	.005	1	view →
THCA	Male	All	−0.306	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

RPL23AP32–LUAD

Open the LUAD breakdown →