RPL23AP31

Across TCGA patient cohorts, RPL23AP31 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,563 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RPL23AP31-associated GO terms across cancer lineages are Ribosomal large subunit assembly, [2Fe-2S] cluster assembly, and [4Fe-4S] cluster assembly. Each is linked with RPL23AP31 in more than 21 cancer types. Because this analysis shows association rather than direction, both RPL23AP31-to-partner and partner-to-RPL23AP31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal large subunit assembly grouped by RPL23AP31-low versus RPL23AP31-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL23AP31→partner) and Y-score (partner→RPL23AP31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Ribosomal large subunit assembly →	+0.052	+0.221	.006	<.001	2	22
DLBC	[2Fe-2S] cluster assembly →	+0.058	+1.210	<.001	<.001	3	20
DLBC	[4Fe-4S] cluster assembly →	+0.081	+1.333	<.001	<.001	3	20
DLBC	Iron-sulfur cluster assembly →	+0.059	+1.257	<.001	<.001	1	21
DLBC	rRNA pseudouridine synthesis →	+0.064	+1.056	<.001	.003	1	19
STAD	Regulation of telomere maintenance in response to DNA damage →	+0.037	+0.213	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,563 associations by consensus.

Ribosomal large subunit assembly by RPL23AP31 expression — ESCA

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