Across TCGA pan-cancer cohorts, RPL23AP14 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RPL23AP14’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RPL23AP14 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL23AP14 is over-expressed in tumor, although a few such as THCA and STAD show the opposite, repressed pattern.

COAD, THCA, and LUAD are the cancer types where RPL23AP14 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL23AP14 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.163	.008	4	view →
THCA	Male	All	−0.122	.008	2	view →
LUAD	Female	II,III,IV	+0.094	.040	2	view →
KIRC	All	All	+0.040	.014	2	view →
STAD	Male	III,IV	−0.233	.016	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: RPL23AP14 RNA expression & survival · all RPL23AP14 data types